Officials in some Gulf Coast states spent the third anniversary of Hurricane Katrina on Friday gearing up for what could be the biggest threat to the region since Katrina hit in 2005.
Hurricane Gustav is poised to pass near or over the Cayman Islands on Friday night and over western portions of Cuba on Saturday. It may approach the U.S. Gulf Coast by Tuesday morning as a Category 2 or 3 hurricane, the National Hurricane Center said Friday.
"Today, on that third anniversary, we've got to be thinking about the future," Mississippi Gov. Haley Barbour said. "As we pray for the best, we're going to prepare for the worst," 
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CNN's John Couwels, Chris Lawrence, Barbara Starr, Eric Marropodi and Kim Segal contributed to this report.
All About Hurricane Katrina • New Orleans
