(CNN) -- Phil Mickelson fired a two-under par 68 in the first round of the St Jude Classic in Memphis -- his first competitive round since wife Amy was diagnosed with cancer last month.
Mickelson is playing in his first PGA Tour event since his wife was diagnosed with cancer last month.
World number two Mickelson had an up-and-down afternoon, mixing birdies and bogeys alike, but a double bogey on the 18th meant he dropped off the leaderboard.
"It was a good way to get started again," Mickelson told reporters. "I'm pleased with the round. I'm not on top of the leaderboard, but the round didn't hurt me at all."
Veteran John Daly also made his US Tour comeback, following the end of his suspension, but he was less than happy with his two-over-par round of 72 that included three bogeys in a row on the back nine.
"That's probably the worst I've putted in five years," Daly said as he walked off the 18th green.
Meanwhile, American Brian Gay holds the first round lead after carding a six-under-par 64, one stroke ahead of fellow American Jimmy Walker and two clear of Sweden's Mathias Gronberg, Jose Maria Olazabal of Spain, Northern Ireland's Graeme McDowell and American pair Rich Beem and Chris Stroud.
Gay, who won the Verizon Heritage tournament in April by a whopping 10 strokes, will book himself a place in next week's U.S. Open with victory this weekend.