Los Angeles, California (CNN) -- Taylor Swift won the biggest Grammy of the night, album of the year for her CD "Fearless."
"This is the story we're going to be telling over and over again, that we got to win album of the year in 2010," Swift said.
Swift also won best country album. She won four Grammys overall.
Beyonce had won a pair of Grammys over Swift, winning the best female pop vocal performance award Sunday night as well as song of the year. That latter honor, a songwriters' award, was given to Beyonce for co-writing "Single Ladies (Put a Ring on It)." List: Major Grammy winners
For the best female pop honor, won for "Halo," the nervous singer thanked her family, "including my husband -- I love you." Beyonce is married to hip-hop star Jay-Z.
The singer won six Grammys all told.
Alternative rock band Kings of Leon upset favorites Beyonce and Swift to win the record of the year Grammy for "Use Somebody."
The win gave the Kings of Leon three Grammys out of four nominations this year, all thanks to last year's "Only by the Night" album. The same album gave them three nominations last year, one of which they won.
"Use Somebody" lost out earlier in the show to Beyonce's "SIngle Ladies" for song of the year.
"The best thing about winning Grammys is really it's the first time our family gets to see the success we're having," Kings lead singer Caleb Followill said backstage. "We're getting my mom wasted."
Winners Sunday night also included Stephen Colbert, the Zac Brown Band and Green Day.
Michael Jackson's two oldest children took the Grammy stage Sunday night to accept their father's lifetime achievement award.
"We are proud to be here to accept this award on behalf of our father," 12-year-old Prince Michael said at the 52nd annual Grammy Awards.
He then thanked "God for watching over us these last seven months and our grandmother and grandfather for their love and support."
Prince Michael also spoke about his father's concern for Earth's environment.
"To all his songs, his message was simple, love," Prince Michael said. "We will continue to spread his message and help the world."
"We love you daddy," he said.
Paris, 11, then spoke: "Daddy was suppose to be here. Daddy was going to perform last year. Thank you. We love you daddy."
Prince Michael and Paris, along with several cousins, wore black suits with red stripes on their pants and red armbands.
The children appeared after a rousing performance of Michael Jackson's "Earth Song," with a recording of Jackson accompanied by live performances from Celine Dion, Usher, Carrie Underwood, Smokey Robinson and Jennifer Hudson.
The Zac Brown Band won best new artist. Lady Gaga, considered by many to be this year's biggest breakout act, was ruled ineligible because she had a song released and nominated last year.
Stephen Colbert won best comedy album for "A Colbert Christmas: The Greatest Gift of All!" Rap/sung collaboration went to Jay-Z, Rihanna and Kanye West.
Green Day won best rock album.
"Now I'm going to do shots with Kings of Leon," Green Day's Billie Joe Armstrong said.
Lady Gaga, whose performance opened the show, won two Grammys presented in the pre-telecast. Her single "Poker Face" beat out songs by the Black Eyed Peas, Madonna and Britney Spears in the best dance recording category. Her CD "The Fame" also won a Grammy for best electronic/dance.