(CNN) -- Syrian rebels have seized most of a military academy outside Aleppo after weeks of fighting with regime troops, a network of opposition activists said Saturday, in the latest sign that government forces are losing ground.
Rebel brigades have had the sprawling military base in a stranglehold for days.
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A rebel commander told CNN in early December that at least 250 government soldiers had defected since the infantry academy came under siege, with most joining the rebel forces.
The Free Syrian Army now has control of most of the base, the opposition Local Coordination Committees for Syria said Saturday.
Heavy clashes were also reported between regime forces and rebel fighters in and around the town of Daraya, near the capital, Damascus.
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Regime forces are shelling parts of the city, which has been under siege for weeks, according to the opposition Syrian Observatory for Human Rights.
The Observatory also reported shelling by government security forces of the northeastern towns of Harasta and Erbeen, in the Damascus suburbs, Saturday morning.
There are also clashes between rebel fighters and regime forces along the main highway that passes southern Damascus, it said.
The LCC reported airstrikes by fighter jets on southern neighborhoods of the capital.
At least 60 people died across the country on Saturday, including 20 in Damascus and its suburbs, the LCC reported.
CNN cannot independently confirm government or opposition claims about violence and casualties as Syria has severely restricted access for journalists.
Syria's Foreign Minister Walid Moallem called for an end to U.S. and European Union sanctions against his country in a meeting with U.N. humanitarian chief Valerie Amos in Damascus on Saturday, according to Syria's official news agency, SANA.
Moaellem said the sanctions were responsible for the Syrian people's suffering and urged the United Nations to condemn them. He also called on Amos for U.N. help to reconstruct infrastructure such as hospitals damaged during the 22-month conflict, SANA said.
The U.N. secretary general's special representative for children and armed conflict, Leila Zerrougui, also arrived in the capital Friday to assess the impact of the conflict on the country's children, the news agency said.
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Zerrougui will meet Syrian officials, U.N. staffers in the country and members of civil society groups during the four-day visit, it said.
SANA also reported that government forces had continued their mission Friday to clear areas and neighborhoods in Deir Ezzor, in the country's east, from "mercenary terrorists."
The Syrian government refers to the rebel forces as terrorists.
U.S. officials said Friday that Syrian President Bashar al-Assad's control is crumbling at an accelerating pace.
"It's at its lowest point yet," said one senior U.S. official with direct knowledge of the latest assessments. U.S. intelligence believes the decline has accelerated in recent weeks. "The trend is moving more rapidly than it has in the past."
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The officials agreed to talk on the condition their names not be used because they were not authorized to discuss the information with the media.
The United States and Germany are sending Patriot missiles and troops to the Turkish border in order to protect their fellow NATO member from potential threats from Syria.
The surface-to-air interceptors would be "dealing with threats that come out of Syria," said U.S. Defense Secretary Leon Panetta Friday. Threats would include Syrian strikes inside Turkey and fighting between the government and rebels that extends into Turkey.
Errant Syrian artillery shells struck the Turkish border town of Akcakale and killed five Turkish civilians in October.
The United States has accused Damascus of launching Scud-type artillery from the capital at rebels in the country's north. One Washington official said missiles came close to the border of Turkey, a staunch U.S. ally.
Syria's government called the accusations "untrue rumors" Friday, according to state news agency SANA. Damascus accused Turkey and its partners of instigating rumors to make the government look bad internationally.
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Reports that the Syrian government may be considering the use of chemical weapons have also heightened international concerns in recent days. Syria denies it has such weapons and says it would not use them even if it did.
The Syrian civil war started in March 2011 when a government crackdown on civilian demonstrators morphed into a fight between the regime and rebels.
The conflict has a proxy element, with Sunni countries such as Turkey, Qatar and Saudi Arabia backing the rebels and Shiite Iran backing the Alawite regime. The Alawite faith is an offshoot of Shiite Islam.
More than 40,000 people have died in the war. The United Nations said on Friday that many Syrians will continue to be killed and maimed after the war ends because of deadly explosives placed in residential areas across the country.
CNN's Arwa Damon, Pierre Meilhan, Yousuf Basil and Amir Ahmed contributed to this report.
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Syrian rebels leave their position in the northwestern town of Maaret al-Numan on Thursday, June 13. The White House said that the Syrian government has crossed a "red line" with its use of chemical weapons and announced it would start arming the rebels.
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Syrian rebels take position in a house during clashes with regime forces in the old city of Aleppo on May 22.
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Rebel fighters fire at government forces in the northern Syrian city of Aleppo on Sunday, May 12.
Searchers use a flashlight as they look for survivors among the rubble created by what activists say was a missile attack from the Syrian regime, in Raqqa province, Syria, on April 25.
A Kurdish fighter from the "Popular Protection Units" (YPG) takes position inside a building in the majority-Kurdish Sheikh Maqsood area of Aleppo, on Apri. 21.
People walk past destroyed houses in the northern Syrian town of Azaz on Sunday, April 21.
Free Syrian Army fighters take positions prior to an offensive against government forces in the Khan al-Assal area, near Aleppo on Saturday, April 20.
Men inspect damage at a house destroyed in an airstrike in Aleppo on April 15.
Syrian and Kurdish rebel fighters walk in the Sheikh Maqsud district of Aleppo on April 14.
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A rebel runs to avoid sniper fire from Syrian government forces in Aleppo on Thursday, April 11.
Syrian rebels observe the movement of Syrian government forces around Al-Kendi hospital in Aleppo on Wednesday, April 10.
Rescue teams and security forces check out the scene of a deadly car bomb explosion in Damascus on April 8.
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A Syrian rebel runs for cover in Deir ez-Zor on April 2.
A rebel checks for snipers across the street toward the Citadel in Aleppo, Syria, on Saturday, March 30, in this photo taken by iReporter Lee Harper.
A Free Syrian fighter mourns the death of a friend in Aleppo on March 30, in this photo taken by iReporter Lee Harper.
A Syrian opposition fighter runs for cover from Syrian army snipers in Aleppo on Wednesday, March 27.
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A Syrian man and his family drive past damaged buildings in Maarat al-Numan, on Wednesday, March 20.
Syrians carry the body of a Syrian army soldier during a funeral ceremony in Idlib province on Tuesday, March 19.
Syrian rebels take position in Aleppo, the largest city in the country, on March 11.
Syrian men search for their relatives amongst the bodies of civilians executed and dumped in the Quweiq River on March 11.
A Free Syrian Army fighter looks back as smoke rises during fighting between rebel fighters and forces loyal to Syria's President Bashar al-Assad on the outskirts of Aleppo on Saturday, March 2.
Residents read Shaam News newspapers published by the Free Syrian Army in Aleppo on March 2.
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A rebel fighter throws a home-made grenade at Syrian government forces in Aleppo on February 16.
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A Syrian woman looks through a bus window in Aleppo on February 14.
Free Syrian Army fighters walk through a dust-filled stairwell in Damascus on February 7.
A Syrian rebel gestures at comrades from inside a broken armored personnel carrier in Al-Yaqubia on February 6.
A rebel fighter throws a hand grenade inside a Syrian Army base in Damascus on February 3.
People stand in the dust of a building destroyed in an airstrike in Aleppo, Syria on February 3.
Free Syrian Army fighters run as they enter a Syrian Army base during heavy fighting in the Arabeen neighborhood of Damascus on February 3.
An unexploded mortar shell fired by the Syrian Army sits lodged in the ground in Damascus on January 25.
Fighters from Fateh al Sham unit of the Free Syrian Army fire on Syrian Army soldiers at a check point in Damascus on January 20.
A Free Syrian Army fighter walks between buildings damaged during Syrian Air Force strikes in Damascus on January 19.
A Syrian rebel fighter tries to locate a government jet fighter in Aleppo on January 18.
Syrian rebels launch a missile near the Abu Baker brigade in Albab on January 16.
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Syrians look for survivors amid the rubble of a building targeted by a missile in Aleppo on January 7.
A father reacts after hearing of a shelling by forces loyal to Syria's President Bashar al-Assad in Aleppo on January 3.
A patient smokes a cigarette at Dar Al-Ajaza psychiatric hospital in Aleppo on December 18, 2012. The psychiatric ward, housing around 60 patients, has lacked the means to function properly since fighting broke out there in July.
Syrians mourn a fallen rebel fighter at a rebel base in the al-Fardos area of Aleppo on December 8.
Members of Liwa (Brigade) Salahadin, a Kurdish military unit fighting alongside rebel fighters, monitor the area in the besieged district of Karmel al-Jabl in Aleppo on December 6.
A member of Liwa Salahadin aims at a regime fighter in the besieged district of Karmel al-Jabl in Aleppo on December 6.
Two young boys sit underneath a washline in a refugee camp on the border between Syria and Turkey near Azaz on December 5.
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Smoke rises in the Hanano and Bustan al-Basha districts in Aleppo on December 1 as fighting continues through the night.
Damaged houses in Aleppo are seen after an airstrike on November 29.
A Syrian rebel mourns the death of a comrade in Maraat al-Numan on November 20.
Syrians protesters stand on Assad's portrait during an anti-regime demonstration in Aleppo on November 16.
A Syrian rebel takes cover during fighting against Syrian government forces in Aleppo on November 15.
Syrian opposition fighter Bazel Araj, 19, sleeps next to his pistol in Aleppo on November 11.
A rebel fighter fires at a Syrian government position in Aleppo on November 6.
A Syrian rebel leaps over debris left in the street while running across a "sniper alley" near the Salahudeen district in Aleppo on November 4.
Rebels hold their position in the midst of a battle on November 3 in Aleppo.
A man cries while being treated in a local hospital in a rebel-controlled area of Aleppo on October 31.
A man is treated for wounds after a government jet attacked the Karm al-Aser neighborhood in eastern Aleppo on October 31.
A Syrian rebel interrogates a handcuffed and blindfolded man suspected of being a pro-regime militiaman in Aleppo on October 26.
Smoke rises from a fuel station following a mortar attack as Syrian women walk on a rainy day in the Arqub neighborhood of Aleppo on October 25.
A Syrian rebel fires at an army position in the Karm al-Jabal district of Aleppo on October 22.
A wounded Syrian boy sits on the back of a truck carrying victims and wounded people to a hospital following an attack by regime forces in Aleppo on October 21.
A man lies on the ground after being shot by a sniper for a second time as he waits to be rescued by members of the Al-Baraa Bin Malek Battalion, part of the Free Syria Army's Al-Fatah brigade, in Aleppo on October 20.
Syrian army soldiers run for cover during clashes with rebel fighters at Karam al-Jabal neighborhood of Aleppo on October 20.
Smoke rises after a Syrian Air Force fighter jet fired missiles at the suburbs of the northern province of Idlib on October 16.
A Syrian opposition fighter stands near a post in Aleppo on October 11.
A Syrian man mourns the death of his father, who was killed during a government attack in Aleppo on October 10.
A rebel fighter is carried by his friends and laid on a gurney to be treated for gunshot wounds sustained during heavy battles with government forces in Aleppo on October 1.
Syrian rebels help a wounded comrade to an Aleppo hospital after he was injured in a Syrian army strike on September 18.
Free Syria Army fighters are reflected in a mirror they use to see a Syrian Army post only 50 meters away in Aleppo on September 16.
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A woman walks past a destroyed building in Aleppo on September 13.
Free Syrian Army fighters battle during street fighting against Syrian army soldiers in Aleppo on September 8.
A Syrian man wounded by shelling sits on a chair outside a closed shop in Aleppo on September 4.
A woman sits in her wheelchair next to her house, damaged by a Syrian air raid, near Homs on August 26.
Members of the Free Syrian Army clash with Syrian army soliders in Aleppo's Saif al-Dawla district on August 22.
A man mourns in front of a field hospital on August 21 in Aleppo.
Wounded civilians wait in a field hospital after an air strike on August 21 in Aleppo.
People pray during the funeral of a Free Syrian Army fighter, Amar Ali Amero, on August 21.
A man cries near the graves of his two children killed during a recent Syrian airstrike in Azaz on August 20.
A Syrian woman holds her dead baby as she screams upon seeing her husband's body being covered following an airstrike by regime forces on the town of Azaz on August 15.
A Syrian rebel runs in a street of Selehattin during an attack on the municipal building on July 23.
Syrian rebels hunt for snipers after attacking the municipality building in the city center of Selehattin on July 23.
Members of the Free Syrian Army's Mugaweer (commandos) Brigade pay their respects in a cemetery on May 12 in Qusayr.
Syrian rebels take position near Qusayr on May 10.
A Free Syrian Army member takes cover in underground caves in Sarmin on April 9.
Rebels prepare to engage government tanks that advanced into Saraquib on April 9.
Men say prayers during a ceremony in Binnish on April 9.
A young boy plays with a toy gun in Binnish on April 9.
A Free Syrian Army rebel mounts his horse in the Al-Shatouria village near the Turkish border in northwestern Syria on March 16, a year after the uprising began.
Syrian refugees walk across a field before crossing into Turkey on March 14.
A rebel takes position in Al-Qsair on January 27.
A protester in Homs throws a tear gas bomb back towards security forces, on December 27, 2011.
A man stands under a giant Syrian flag outside the Umayyad Mosque in Damascus on December 24, 2011.
A member of the Free Syrian Army looks out over a valley in the village of Ain al-Baida on December 15, 2011.
Members of the Free Syrian Army stand in an valley near the village of Ain al-Baida, close to the Turkish border, on December 15, 2011.
Displaced Syrian refugees walk through an orchard adjacent to Syria's northern border with Turkey on June 14, 2011, near Khirbet al-Jouz.
A Syrian man holds up a portrait of President Bashar al-Assad during a rally to show support for the president in Damascus on April 30, 2011.
Syrians rally to show their support for President Bashar al-Assad in Damascus on April 30, 2011.
A screen grab from YouTube shows thick smoke rising above as Syrian anti-government protesters demonstrate in Moaret Al-Noman on April 29, 2011.
A screen grab from YouTube shows Syrian anti-government protesters run for cover from tear gas fired by security forces in Damascus on April 29, 2011, during the "Day of Rage" demonstrations called by activists to put pressure on al-Assad.
Syrians wave their national flag and hold portraits of al-Assad during a rally to show their support for their leader in Damascus on March 29, 2011.
A woman sits by the hospital bed of a man allegedly injured when an armed group seized rooftops in Latakia on March 27, 2011, and opened fire at passers-by, citizens and security forces personnel according to official sources.
Syrian protesters chant slogans in support of al-Assad during a rally in Damascus on March 25, 2011.
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