Part of complete coverage on
Maria Sharapova out of U.S. Open
August 22, 2013 -- Updated 1325 GMT (2125 HKT)
World No. 3 Maria Sharapova was promoting her range of candy in New York ahead of the tournament.
- Maria Sharapova pulls out of the U.S. Open with a shoulder injury
- The world No. 3 was a champion at Flushing Meadows in 2006
- She is replaced as third seed by Poland's Agnieszka Radwanska
- Former U.S. No. 1 Mardy Fish to miss the U.S. Open due to health issues
(CNN) -- Maria Sharapova has been forced out of the U.S. Open with a right shoulder injury, continuing a turbulent few months for the four-time grand slam winner.
The world No. 3 is suffering from bursitis, which occurs when a small, fluid-filled sac forms under the skin.
"I have done everything I could since Wimbledon to get myself ready but it just wasn't enough time," Sharapova said in a statement released on her website.
"I have done many tests, received several opinions and it all comes down to taking the proper amount of time to heal my shoulder injury properly.
It's certainly not an easy decision to make ahead of one of my favorite tournaments, but I know it's the right one that will get me back on the courts soon.
Japan's 'rock star' tennis pro
Tennis baby takes Internet by storm
Marion Bartoli on Wimbledon triumph
"I plan on taking the next few weeks off, receiving proper treatment and rehabilitation. I will miss being part of the US Open, but can't wait for next year."
Read: What does women's tennis owe Billie Jean King?
After losing to Portuguese qualifier Michelle Larcher De Brito in the second round of Wimbledon in June, the Russian ended her three-year partnership with coach Thomas Hogstedt.
She then hired legendary eight-time grand slam winner Jimmy Connors as his replacement, but that was ended after just one match, her second-round defeat to American starlet Sloane Stephens at the Western and Southern Open in Cincinnati.
The 2006 U.S. Open champion had reportedly agreed to have her father coach her throughout the year's final grand slam.
Read: U.S. Open to have two retractable roofs
Sharapova grabbed the headlines earlier this week amid suggestions she was set to change her name to "Sugarpova" for the duration of tournament, a marketing stunt designed to promote her candy range.
Her representatives, however, told CNN that it would be "too complicated."
In Sharapova's absence Poland's Agnieszka Radwanska will be instated as the third seed for Thursday's draw.
Home fans suffered a blow with the news that American Mardy Fish has withdrawn from tournament as he continues to struggle with ongoing health issues.
The former world No. 7 has been battling a heart condition which first came to light in May 2012 and required him to have surgery to correct faulty electrical connections within his heart.
Fish has already missed the Australian and French Opens and Wimbledon this year.
Earlier this week he was forced to withdraw from his match with Jarkko Nieminen at the Winston-Salem Open.
"Friends, unfortunately my health won't allow me to compete this year at the US Open. Thank you for all your support," the 31-year-old announced on his official Twitter account.
Fish reached the fourth round at Flushing Meadows in each of the last three years and was a quarterfinalist in 2008.
Today's five most popular stories
Part of complete coverage on
December 16, 2014 -- Updated 1208 GMT (2008 HKT)
Rafael Nadal's body might be giving him a few problems, but his mind remains as strong as ever. Will the Spaniard add to his haul of 14 grand slam titles?
November 24, 2014 -- Updated 1342 GMT (2142 HKT)
A year that began in uncertainty for Roger Federer ended with a historic title for the 17-time grand slam champion and his country.
November 27, 2014 -- Updated 1716 GMT (0116 HKT)
The Scot has served up a few changes to his support team in 2014 but there's one person who isn't going anywhere -- his new fiancée Kim Sears.
September 11, 2014 -- Updated 1248 GMT (2048 HKT)
His distinctive crocodile logo is seen on clothing all over the world, but Rene Lacoste also left a lasting legacy in the development of tennis.
September 9, 2014 -- Updated 0636 GMT (1436 HKT)
Marin Cilic follows in the footsteps of his coach Goran Ivanicevic by claiming a grand slam crown for Croatia, winning the U.S. Open.
September 14, 2014 -- Updated 1334 GMT (2134 HKT)
Serena Williams is without peer in the modern women's game and now she is on a par with two American tennis legends from the past.
September 2, 2014 -- Updated 1321 GMT (2121 HKT)
Over the course of her remarkable life, Althea Gibson was many things to many people -- but it was tennis where she really left her mark.
August 27, 2014 -- Updated 1145 GMT (1945 HKT)
Canada and tennis? Really? Yup. The North American tennis power balance is swinging away from the States.
August 21, 2014 -- Updated 1252 GMT (2052 HKT)
As a player he was as fiery as his hair -- and as Novak Djokovic's coach, Boris Becker says he has to battle to keep his emotions in check.
August 20, 2014 -- Updated 1102 GMT (1902 HKT)
Tennis great Boris Becker says he was stunned by the level of criticism he received after being appointed as Novak Djokovic's coach.
July 25, 2014 -- Updated 1101 GMT (1901 HKT)
"I didn't cry once when I practiced in front of the mirror," says Martin Emmrich. But the nerves kicked in when he got down on one knee on court.
June 30, 2014 -- Updated 1135 GMT (1935 HKT)
When Agnieszka Radwanska refused to look her opponent in the eye after losing at Wimbledon, it raised more than eyebrows.
June 23, 2014 -- Updated 0114 GMT (0914 HKT)
It's 10 years since a teenage Maria Sharapova became the darling of Wimbledon's hallowed Center Court, launching herself as a star.
May 23, 2014 -- Updated 0746 GMT (1546 HKT)
He's regularly voted France's favorite famous person, but many of the nation's youth have "no idea" about his glorious sporting past
April 29, 2014 -- Updated 1555 GMT (2355 HKT)
Five-time grand slam champion Martina Hingis has followed her mom into a coaching role, setting up a new tennis academy in Barcelona, Spain.