Nobel medical prize goes to 2 Americans, 1 German
October 11, 2013 -- Updated 1147 GMT (1947 HKT)
The Nobel Prize in physiology or medicine starts a week of announcements in Stockholm, Sweden.
- Scientists solved a mystery of how cells deliver molecules
- All three work at American universities
- Prize announcements continue with physics Tuesday
- Each prize, endowed by Alfred Nobel in 1895, comes with $1.2 million
(CNN) -- Two Americans and a German shared the Nobel Prize in physiology or medicine this year.
Americans James E. Rothman and Randy W. Schekman, and German Thomas C. Sudhof were awarded the prize Monday for discoveries of how the body's cells decide when and where to deliver the molecules they produce.
The Nobel Assembly said the three "have solved the mystery of how the cell organizes its transport system."
Their work focuses on tiny bubbles inside cells called vesicles, which move hormones and other molecules within cells and sometimes outside them, such as when insulin is released into the bloodstream.
Winners of the 2013 Medicine Nobel Prize
Yale University professor Robert Shiller, famous for his warnings of the housing and Internet bubbles, is one of three Americans who were awarded the Nobel Prize in economics on Monday, October 14. The Nobel committee recognized Shiller and University of Chicago professors Eugene Fama and Lars Peter Hansen for their work on the pricing of financial assets.
Photos: Nobel Prize winners of 2013
Disruptions of this delivery system contribute to diabetes, neurological diseases and immunological disorders.
Rothman, a professor at Yale University, detailed how protein machinery allows vesicles in cells to fuse with their targets to permit the transfer of molecular cargo.
Schekman, a professor at the University of California, Berkeley, was honored for discovering a set of genes required for the "vesicle traffic."
Sudhof, a professor at Stanford University, showed how vesicles are instructed precisely when to release molecules.
Schekman and Sudhof also are investigators at Howard Hughes Medical Institute.
Monday's ceremony at the Karolinska Institute in Stockholm, Sweden, will be followed by the announcement of the physics prize Tuesday, the chemistry prize Wednesday and the economics prize on October 14.
The Nobel Peace Prize will be awarded in Oslo, Norway, on Friday. The prize for literature will be awarded on a date to be announced later. Each prize comes with 8 million Swedish kronor ($1.2 million).
Swedish industrialist Alfred Nobel created the prizes in 1895 to honor work in physics, chemistry, literature and peace. The first economics prize was awarded in 1969.
In 2012, the medical Nobel Prize was awarded to Sir John B. Gurdon of England and Shinya Yamanaka of Japan for work on reprogramming cells. Their work paved the way for treatment breakthroughs.
What to know: Nobel prizes
Part of complete coverage on
December 10, 2013 -- Updated 1900 GMT (0300 HKT)
Presidents and prime ministers, celebrities and royals joined tens of thousands of South Africans to pay tribute to Nelson Mandela.
Syrian refugees fleeing into Lebanon tell CNN's Nick Paton Walsh how they stepped over dead bodies in their flight -- and now face the a biting winter.
December 11, 2013 -- Updated 1629 GMT (0029 HKT)
It looked plausible to most, but to deaf people watching the Mandela memorial -- it was all nonsense. The interpreter has been dubbed "a fake."
December 11, 2013 -- Updated 0541 GMT (1341 HKT)
They hoped for playful weekend outing in the snow. The moments of adventure dissolved into a fight for survival for the family of six.
December 11, 2013 -- Updated 1714 GMT (0114 HKT)
Yahoo's teen star Nick D'Aloisio sells the new digital future -- with vanishing content.
December 11, 2013 -- Updated 1328 GMT (2128 HKT)
Denmark's PM Helle Thorning-Schmidt made headlines when she snapped a selfie with PM David Cameron and President Barack Obama.
December 11, 2013 -- Updated 1311 GMT (2111 HKT)
Mars kits, a triple nipple baby bottle and extinct animal DNA are just some of things you'd find inside the "99¢ Store of the Future."
December 11, 2013 -- Updated 0958 GMT (1758 HKT)
They say necessity is the mother of invention. Here are 11 of the most mind-boggling inventions ever submitted to the U.S. patent office.
December 9, 2013 -- Updated 2311 GMT (0711 HKT)
Until he returned home this weekend, Merrill Newman -- an American held in North Korea -- had no idea what a story he'd become.
December 10, 2013 -- Updated 1611 GMT (0011 HKT)
The Web is set to change our lives over the next decade. This will also question the use of personal data and balancing new powers with ethics.
December 11, 2013 -- Updated 1756 GMT (0156 HKT)
Browse through images you don't always see in news reports, taken by CNN teams all around the world.
He was imprisoned for life but that did not quiet him. Nelson Mandela became South Africa's first black president, and an icon and inspiration.
Today's five most popular stories