Story highlights

Jeep carrying suspected militants blows up on highway near Damascus

Mostly government-held cities were targeted in ISIS attacks

CNN  — 

Deadly explosions rocked Syria Monday, hours after the United States and Russia discussed an end to the violence during G20 talks.

At least 40 people were killed and dozens more wounded in a series of coordinated explosions across the country, Syrian state media reported.

The blasts happened in government-held areas of Damascus, Homs and Tartous, as well as at a Kurdish checkpoint in Hassakah.

ISIS claimed responsibility for the attacks, according to a statement by the ISIS-affiliated Amaq agency.

The deadly toll

Of those killed, 30 died in two explosions on a main highway bridge near Tartous, on the Mediterranean coast.

Another four people died when a car bomb exploded at an army checkpoint in the government-held al-Zahraa neighborhood in Homs, according to Gov. Talal Barazi.

A jeep carrying six suspected militants blew up after a soldier stopped the vehicle on a highway near Damascus. The soldier was killed. Police Gen. Jamal A-Bitar told Syrian TV he believes the car was on its way to carry out an attack in the capital.

And in the Kurdish-controlled northeastern city of Hassakah, a suicide bomber on a motorcycle killed five Kurdish security forces at a checkpoint.

US, Russia talks on Syria

The blasts come as high-level talks between the United States and Russia aimed at ending violence in Syria ended without an agreement, a US official said Monday.

The meeting between US Secretary of State John Kerry and his Russian counterpart Sergey Lavrov on the sidelines of the G20 summit in Hangzhou, China, failed to resolve differences and left the Syrian question unanswered, the official said.

US President Barack Obama and Russia's President Vladimir Putin leave after posing for a photo ahead of a bilateral meeting on the sidelines of the 70th session of the UN General Assembly at the United Nations headquarters on September 28, 2015 in New York. AFP PHOTO/MANDEL NGAN        (Photo credit should read MANDEL NGAN/AFP/Getty Images)
No Syria deal between US and Russia
01:48 - Source: CNN

Later in the day, US President Barack Obama and Russian President Vladimir Putin also met for an additional discussion on Syria. The leaders directed Kerry and Lavrov to reach an agreement in the coming days, according to a senior White House official.

Why Obama shouldn’t expect much from the G20

Turkey clears ISIS from Syrian border

turkey syria isis reclaim_00003606.jpg
Turkey says it has reclaimed ISIS controlled region
01:02 - Source: CNN

Meanwhile, Turkey is claiming success in its campaign to eradicate ISIS from its border regions.

The terror group has reportedly lost control of the last strip of its territory along the Syrian-Turkish border, according to sources and the Turkish state-run news agency Anadolu.

The border town of Jarablus, which Syrian rebels and Turkish forces recently recaptured from the terror group, is a critical location for supplies, money and fighters coming in and out of ISIS-held areas.

Azaz is another key border city that was formerly held by ISIS.

Inside Jarablus: What happens when ISIS loses control of a city

The developments would be a major setback for ISIS, choking off supply lines for the terror group.

CNN’s Schams Elwazer, Kareem Khadder, Kevin Liptak, Tim Hume, Hamdi Alkhshali and Chandrika Narayan contributed to this report.