Several times per hour the crew launches between four and 10 fighter jets, many of them armed and headed for Iraq and Syria.
France recently moved the Charles de Gaulle -- or "CDG" as the crew calls it -- to the Mediterranean Sea, close to the Syrian coast.
Boasting a squadron of 24 Rafale M jets, the ship will triple France's firepower against ISIS from 12 aircraft to 36.
"The aim is to help the Iraqi forces on the ground to fight against ISIS," explained senior pilot Marc, who for security reasons can only be identified by his first name.
How will the jets operate?
The Rafale M will fly three different types of missions. First up is "Close Air Support," where jets essentially loiter around the airspace waiting for allied ground forces to call on them to hit ISIS targets.
All strikes must go through the central coalition targeting center, led by the US, and be approved by the French military.
Secondly, the Rafales will conduct pre-planned air strikes against ISIS facilities and leaders.
And thirdly, the aircraft will take pictures of ISIS installations and personnel, to be used in later strikes.
Eyes on Mosul
While the CDG strike group will be targeting ISIS in both Iraq and Syria, their focus right now is very much on the terror group's stronghold of Mosul.
"The fall of ISIS is our ultimate goal," explained the ship's admiral, Olivier Lebas.
"And this goes with the liberation of Mosul and Raqqa."
Indeed, the US-led anti ISIS coalition is currently gearing up for a final showdown against ISIS in Mosul, the largest urban stronghold the terror group holds.
A mix of Iraqi security forces, Kurdish and Arab fighters, as well as supporting US and French personnel, have already taken significant ground around Mosul and the final offensive
is believed to be imminent.
Where does France fit into ISIS offensive?
France has been the victim of ISIS terror like no other European nation.
The attacks have not only prompted the country's military action in the Middle East, but a profound sense of purpose in the CDG crew.
"For me, it's about helping to prevent any more terrorist attacks in France -- where our families and relatives live," explained Commander Marc.
"That is very important for all the people on the Charles and in my squadron."
The US-French relationship
France is America's strongest European ally in the fight against ISIS, with the Charles de Gaulle also uniquely capable of working in sync with US forces in the region.
The layout of the flight deck, with a steam-powered launching catapult system and arrested landing ropes, is identical to US naval ships.
As such, the Charles de Gaulle's crew frequently work with their American counterparts.
A constant state of readiness
Around 95% of the ship's aircraft are ready for combat at any given time, said the officer in charge of bombs and maintenance, Frigate Captain Lois, who for security reasons can only be identified by his first name.
"We need to have exactly the same capability as when we are on land," he added.
As the coalition ramps up its pressure on ISIS, the Charles de Gaulle crew must also constantly refine its operations to keep up with the fast tempo of activity.
France's only aircraft carrier has now become the country's prime weapon as it looks to unseat ISIS from Iraq's second largest city -- and ultimately destroy the group altogether.