About 69,000 Rohingya Muslims have fled Myanmar's Rakhine State since the outbreak of violence on October 9, according to the United Nations.
Around one million Rohingya live in Myanmar but the government doesn't recognize them as citizens, and they're considered to be among the most oppressed people in the world.
Reports of killings, rapes and destruction of homes have poured out of the state but are unable to be confirmed due to entry restrictions imposed by the Myanmar government.
"They are good people, they are not Christians, they are peaceful people, they are our brothers and sisters and for years they have been suffering," Pope Francis said during his address.
"They are being tortured and killed."
Francis called on those in attendance to join him in prayer for "our Rohingya brothers and sisters who are being chased from Myanmar and are fleeing from one place to another because no one wants them."
Child murder alleged in Rakhine State
The Pope's statement comes less than a week after the United Nations released a report
which alleged widespread brutal killings and rapes taking place inside Rakhine State.
The report was based on interviews with 220 Rohingya Muslims who fled from Myanmar into Bangladesh.
One young girl told interviewers her father was killed before her eyes, before her mother was raped and then thrown into a house to burn to death.
Others described children as young as five having their throats cut by soldiers.
Myanmar government spokeswoman Aye Aye Soe said they had seen the report and were "very concerned about the allegations."
"The Investigation Commission headed by the Vice President will look into it. If evidences of violations are found we will definitely take action on them," she told CNN via email.
The recent violence began after a group of Rohingya attacked a Myanmar border pos
t on October 9, killing nine guards.
In response, the government began "clearance operations" to find the attackers, which has left more than 100 people
UN High Commissioner for Human Rights Zeid Ra'ad Al Hussein said Myanmar security forces may have committed "crimes against humanity