Note: All links within
content go to MayoClinic.com
Diseases and Conditions
Hepatitis A
From MayoClinic.com
Special to CNN.com Introduction Hepatitis A is a highly contagious liver infection caused by the hepatitis A virus (HAV). Although not usually as serious as other types of viral hepatitis, hepatitis A causes inflammation that affects your liver's ability to function. You're most likely to contract hepatitis A from contaminated food or water or from close contact with someone who's already infected — even if that person doesn't appear sick. Some people who are infected never develop signs and symptoms, but others may feel as if they have a severe flu. Mild cases of hepatitis A don't require treatment, and most people who are infected recover completely with no permanent liver damage. Unlike hepatitis B and C, hepatitis A doesn't develop into chronic hepatitis or cirrhosis — both potentially fatal conditions. Practicing good hygiene — including washing your hands often — is one of the best ways to protect against hepatitis A. Effective vaccines are available for people who are most at risk. Signs and symptoms Some people may have hepatitis A and never develop signs or symptoms. Young children, especially, tend to have mild cases, but symptoms in older children and adults are likely to be more severe. In general, you'll have the virus for up to one month before developing any problems. When signs and symptoms appear, they often come on suddenly, and you may mistake them for intestinal flu (gastroenteritis). They include:
You also may experience yellowing of your skin and the whites of your eyes (jaundice). Not all people with hepatitis A develop jaundice. You'll likely regain more energy after signs and symptoms disappear, and your liver may heal completely within one or two months. Some people with hepatitis A have relapses over a six- to nine-month period. Causes Your liver is located on the right side of your abdomen, just beneath your lower ribs. It performs more than 500 functions, including processing most of the nutrients absorbed from your intestines, removing drugs, alcohol and other harmful substances from your bloodstream, and manufacturing bile — the greenish fluid stored in your gallbladder that helps digest fats. Your liver also produces cholesterol, blood-clotting factors and certain other proteins. Because of the complexity of the liver and its exposure to so many potentially toxic substances, it would seem especially vulnerable to disease. But the liver has an amazing capacity for regeneration — it can heal itself by replacing or repairing injured cells. It's also constructed so that healthy cells will take over the function of damaged cells, either indefinitely or until the damage has been repaired. Yet in spite of this, your liver is prone to a number of diseases, including viral hepatitis. Hepatitis A virus is one of six currently identified strains of viral hepatitis — the others are B, C, D, E and G. The strains differ in severity and in the way they spread. HAV is usually transmitted via the fecal-oral route. That means that someone with the virus handles food you eat without washing his or her hands after using the toilet. You can also contract the virus by drinking contaminated water, eating raw shellfish from water polluted with sewage or being in close contact with a person who's infected — even if that person has no signs or symptoms. In fact, the disease is most contagious before signs and symptoms ever appear. Risk factors You're at increased risk of hepatitis A if you:
In general, food handlers, health care workers, children under age 2 and children who attend child care are not at increased risk of contracting HAV. Although outbreaks of hepatitis A sometimes occur in child care settings, they can be prevented if workers practice good hygiene. Screening and diagnosis See your doctor if you have symptoms of hepatitis A or think you may have been exposed to the virus. Tests can accurately diagnose whether you've been infected. Blood tests can detect the presence of hepatitis by measuring:
Pinpointing hepatitis In addition, you continue to have antibodies even after you recover. For that reason, the presence of some antibodies doesn't necessarily indicate an active infection. Complications In most cases of hepatitis A, the liver heals completely in a month or two with no lasting damage. Furthermore, the virus doesn't remain in your body once you've recovered. Older adults and people with other medical problems, such as congestive heart failure, diabetes and anemia, may take longer to recover and are likely to have a more serious course of the disease. In rare cases, fulminant hepatitis — a life-threatening condition that causes liver failure — may develop. Especially at risk are people with chronic liver disease or a liver transplant. In addition, some studies suggest that the inflammation triggered by hepatitis A may contribute to hardening of the arteries (atherosclerosis) — the gradual buildup of hardened deposits in your arteries. Treatment No specific treatment exists for hepatitis A. Instead, the main focus is on making sure you get adequate nutrition and avoid any permanent liver damage. If you're nauseated, eating small snacks throughout the day instead of three large meals may help. Soft, easily digested foods, such as soup or broth, yogurt and toast, may be the most appealing. You may also find you can tolerate food better in the morning than later in the day. As soon as you've received a diagnosis of hepatitis A, talk to your doctor about any medications you take, including those you buy over-the-counter. Your doctor may recommend stopping or changing some of them. Also, avoid drinking alcohol during the acute phase of your illness. Even after you've recovered, don't mix alcohol and acetaminophen (Tylenol, others); doing so can cause liver damage even in people who haven't had hepatitis. Prevention Hepatitis A is highly contagious. Preventing the spread of the virus involves protecting both yourself and others from infection. Protecting yourself
Protecting others
Complementary and alternative medicine In Europe, the herb milk thistle (Silybum marianum) has been used for centuries to treat jaundice and other liver disorders. Today, scientific studies have confirmed that the chief constituent of milk thistle, silymarin, may aid in healing and rebuilding the liver. Silymarin seems to stimulate the production of antioxidant enzymes that help the liver neutralize toxins. It also seems to increase the production of new liver cells and may even improve the severe scarring of cirrhosis. But although milk thistle can help the liver, it won't cure hepatitis, and it won't protect you from contracting the virus. Milk thistle is available in capsules or alcohol-free extracts. Check with your doctor before trying this or any other herb, to make sure it won't interact with other medications you're taking. September 12, 2005 |