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Diseases and Conditions
Ascariasis
From MayoClinic.com
Special to CNN.com Introduction Ascariasis is a type of roundworm infection. Roundworms are parasites that use your body as a host to stay alive and reproduce, maturing from eggs to adult worms inside your body. Ascaris eggs are microscopic, but the adult worms are the largest of the intestinal roundworms, reaching lengths up to 40 centimeters, or about 15 inches. Ascariasis is the most common type of roundworm infection in humans, infecting approximately 25 percent of the world's population. The highest rates of infection occur in developing countries. In the United States, ascariasis is more common in rural areas with warm climates, with a higher infection rate in the South. Most of the time, ascariasis causes no symptoms, or only mild stomach or digestive problems. But when your body is infested with hundreds of worms, more serious symptoms and complications can occur. The good news is that ascariasis can be treated effectively with medication. There also are simple steps you can take to prevent ascariasis, mostly involving good hygiene and proper sanitation. Signs and symptoms Mild ascariasis — with only a few parasites in your body — may cause no symptoms. Symptoms occur with moderate or heavy infestations, sometimes progressing as the parasite migrates through your body. After you ingest ascaris eggs, they hatch in your intestine and the larvae migrate into your lungs. At this stage, you may experience symptoms similar to pneumonia, including:
The ascaris larvae eventually reach your throat, where they are coughed up and then swallowed. They then enter the intestine, where they mature and mate. In mild or moderate ascariasis, the intestinal infestation can cause:
If you have a heavy intestinal infestation — a large number of worms — you may experience:
Causes About two months after you first get ascariasis, the mature worms begin laying eggs in your intestine. These microscopic eggs travel through your digestive system and eventually can be found in your feces. Eggs require 10 to 14 days in soil at warm temperatures to become capable of infecting a new host, and can remain viable in the soil for up to six years. When the eggs are ingested, the life cycle begins again. Adult worms can live up to two years, and female worms can produce more than 200,000 eggs daily. The parasite can be transmitted when infected human feces are mixed with soil. In many developing countries human feces are used for fertilizer, or poor sanitary facilities allow human waste to mix with local soil in yards, ditches and fields. The eggs can survive in soil for years to reinfect members of the community. The eggs infect their hosts when humans eat the contaminated vegetables and fruit grown in that soil. Risk factors Risk factors for ascariasis include:
When to seek medical advice If you have gastrointestinal problems that won't go away, such as abdominal pain, diarrhea or nausea, consult your doctor. However, if you have only mild ascariasis, you may never need medical attention. While symptomatic infections usually warrant treatment, infections with no symptoms typically don't need to be treated. In some cases, ascariasis will resolve on its own. This occurs when there are no male worms to mate with females and the females eventually die. Screening and diagnosis About two months after you ingest ascaris eggs, the ascaris worms mature and begin laying thousands of eggs a day. These eggs travel through your digestive system and eventually can be found in your stool. To diagnose ascariasis, your doctor will examine your stool for the microscopic ascaris eggs and larvae. In heavy infestations, it's possible to find worms after you cough or vomit, and the worms can come out of other body openings, such as your mouth or nostrils. If you notice anything resembling a worm when you cough or vomit, or if one emerges from your nose or mouth, keep it to let your doctor examine it. Complications Complications related to typical ascariasis are rare. However, potentially dangerous complications can develop if you have a heavy infestation.
Treatment Anti-parasite (antihelminthic) medications are the first line of treatment against ascariasis. The most common are mebendazole (Vermox), albendazole (Albenza) and pyrantel (Antiminth, Pin-Rid). These medications work by killing the adult worms as well as the larvae and eggs to prevent reinfection. You may have mild gastrointestinal side effects during the course of treatment, and you may need to take multiple doses to get rid of the infestation completely. Surgery Prevention The best defense against ascariasis is good hygiene and common sense. Follow these tips to avoid infection:
February 20, 2006 |