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Diseases and Conditions
Keratosis pilaris
From MayoClinic.com
Special to CNN.com

Introduction

Keratosis pilaris is a harmless skin disorder that causes small, acne-like bumps. Although it isn't serious, keratosis pilaris can be frustrating because it's difficult to treat.

Keratosis pilaris results from a buildup of protein called keratin in the openings of hair follicles in the skin. This produces small, rough patches, usually on the arms and thighs. Though quite common with young children, keratosis pilaris can occur at any age.

Many people are bothered by the goose flesh appearance of keratosis pilaris, but it doesn't have long-term health implications and occurs in otherwise healthy people.

Keratosis pilaris usually resolves without treatment. But if you're concerned about the appearance of your skin, your doctor can help you determine the best course of treatment, which includes self-care measures and medicated creams.

Signs and symptoms

Keratosis pilaris causes small, acne-like bumps, which usually appear on the upper arms, legs or buttocks; they usually don't hurt or itch. The bumps create rough patches and give skin a goose flesh or sandpaper appearance. Typically, patches are skin colored, but they can, at times, be red and inflamed.

Keratosis pilaris can also appear on the face, where it closely resembles acne. The small size of the bumps and its association with dry, chapped skin distinguish keratosis pilaris from pustular acne. Unlike elsewhere on the body, keratosis pilaris on the face may leave small scars.

Though quite common with young children, keratosis pilaris can occur at any age. It may improve, especially during the summer months, only to later worsen. Gradually, keratosis pilaris resolves on its own.

Causes

Keratosis pilaris results from the buildup of keratin — a hard protein that protects your skin from harmful substances and infection. The keratin forms a horny plug that blocks the opening of the hair follicle. Usually many plugs form, causing patches of rough, bumpy skin.

Why keratin builds up is unknown. But it may occur in association with genetic diseases or with other skin conditions, such as ichthyosis vulgaris or atopic dermatitis. Keratosis pilaris also occurs in otherwise healthy people. Dry skin tends to worsen the condition.

When to seek medical advice

Keratosis pilaris isn't a serious medical condition, and treatment usually isn't necessary. However, if you're concerned about the appearance of your skin, consult your family doctor or a dermatologist. He or she can often make a diagnosis by examining your skin and the characteristic horny plugs.

Treatment

No single treatment universally improves keratosis pilaris. But most options, including self-care measures and medicated creams, focus on softening the keratin deposits in the skin.

Prescription medications used to treat keratosis pilaris include:

  • Ammonium lactate (Lac-Hydrin). Available in a cream or lotion, 12 percent ammonium lactate reduces roughness and softens the keratin plugs. It won't, however, lessen the redness caused by the condition.
  • Urea (Carmol, Keralac). Urea moisturizes and softens dry, rough skin. It also helps loosen and remove the dead skin cells. Side effects include redness, stinging and skin irritations.
  • Topical corticosteroids. These anti-inflammatory drugs help decrease cell turnover by suppressing the immune system. Low-potency corticosteroid ointments are usually recommended for sensitive areas such as your face and for treating widespread patches. Doctors usually prescribe corticosteroids for short-term treatment or for temporary relief of symptoms. They aren't used as long-term treatments because of potential side effects.
  • Topical retinoids. Derived from vitamin A, retinoids work by promoting cell turnover and preventing the plugging of the hair follicle. Retinoids may be an effective treatment, but they can cause bothersome skin irritations, such as severe dryness, redness and peeling. Tretinoin (Retin-A Micro, Avita) and tazarotene (Tazorac) are examples of topical retinoids.

Using a medication regularly may improve the appearance of your skin. But if you stop, the condition returns. And even with medical treatment, keratosis pilaris tends to persist for years.

Self-care

Although self-help measures won't cure keratosis pilaris, they may help improve the appearance of your skin. You may find these measures beneficial:

  • Be gentle when washing your skin. Vigorous scrubbing or removal of the plugs may only irritate your skin and aggravate the condition.
  • After washing or bathing, gently pat or blot your skin dry with a towel so that some moisture remains on the skin.
  • Apply the moisturizing lotion or lubricating cream while your skin is still moist from bathing. Choose a moisturizer that contains urea or propylene glycol, chemicals that soften dry, rough skin.
  • Apply an over-the-counter product that contains lactic acid twice daily. Lactic acid helps remove extra keratin from the surface of the skin.
  • Use a humidifier to add moisture to the air inside your home. Low humidity dries out your skin.

August 02, 2006

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