Scientists are using the Concordia research station in Antarctica to research the effects of long space missions. In winter, no sunlight is seen for four months and the typical crew of 12 live in complete isolation.
The next goal for space exploration is for humans to travel to Mars. Antarctica provides a good analogue to research some of the physical and psychological challenges of during long-duration spaceflight.
Living in this white space is, in many ways, similar to living on another planet. The isolation and low oxygen are aspects of life astronauts will have to endure to explore our Solar System.