PSG manager Laurent Blanc made numerous changes with one eye on Tuesday's last-16 Champions League tie against Chelsea.
Leading marksmen Zlatan Ibrahimovic and captain Thiago Silva were the two most obvious absentees while the likes of Angel Di Maria and Marco Verratti started on the bench.
Uruguayan striker Edinson Cavani spurned the Parisian's best chance of the afternoon, missing when presented with a golden opportunity early in the second half.
Lille goalkeeper, Vincent Enyama, also saved from Lucas, Jean-Kevin Augustin and Layvin Kurzawa to keep the Parisians out.
Despite being unable to take the win, PSG remains a comfortable 25 points ahead of second placed Monaco.
"We needed to avoid injuries and we did so. All that was missing was the two points we dropped," PSG manager Laurent Blanc told reporters after the match.
"We could have played better but I can't knock my players for their spirit. We had five or six clear chances but Lille never gave up and I am quite satisfied. This match was difficult to play for multiple reasons."
Chelsea's "Zorro" team skewers Magpies
Chelsea prepared for it's Parisian date with an emphatic 5-1 home victory at home to Newcastle United.
Manager Guus Hiddink had said before the game his side were a "Zorro team" in reference to the face mask been worn by striker Diego Costa to protect further damage to a facial injury he sustained in training this week.
Teammates Cesc Fabregas, Cesar Azpilicueta and Nemanja Matic have all donned face guards, which bear a striking resemblance to the mysterious mask worn by the fictional comic book hero, at different stages this season.