FDA requires 'black box' warning on painkillers

By Nadia Kounang, CNN

Updated 1754 GMT (0154 HKT) June 2, 2016

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Ibuprofen falls into the class of drugs known as NSAIDs (nonsteroidal anti-inflammatory drugs). Sold under brand names including Motrin or Advil, it's used to treat minor aches and pains and reduce fever. It may be prescribed in stronger doses. It comes in tablet form as well as in chewable tablets, liquid suspensions and concentrated liquid drops. People who take NSAIDs may have a higher heart attack or stroke risk than those who do not, according to the <a href="http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682159.html" target="_blank">National Institutes of Health</a>. The medication can also cause ulcers, bleeding or holes in the stomach and intestine for some people. The risk may be higher if you take NSAIDs for a long time, are older or in poor health, and have three or more alcoholic drinks per day.
Photos: Photos: A guide to (legal) pain relief
Ibuprofen – Ibuprofen falls into the class of drugs known as NSAIDs (nonsteroidal anti-inflammatory drugs). Sold under brand names including Motrin or Advil, it's used to treat minor aches and pains and reduce fever. It may be prescribed in stronger doses. It comes in tablet form as well as in chewable tablets, liquid suspensions and concentrated liquid drops. People who take NSAIDs may have a higher heart attack or stroke risk than those who do not, according to the National Institutes of Health. The medication can also cause ulcers, bleeding or holes in the stomach and intestine for some people. The risk may be higher if you take NSAIDs for a long time, are older or in poor health, and have three or more alcoholic drinks per day.
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This compound can ease minor muscle, back, tooth and joint pain and reduce fever. Sold under brand names such as Tylenol, Liquiprin and Panadol, it <a href="http://cid.oxfordjournals.org/content/31/Supplement_5/S202.full" target="_blank">works by regulating</a> the part of your brain that controls your body's temperature and inhibits the synthesis of prostaglandin in the central nervous system. <a href="http://www.cnn.com/2015/04/15/health/study-acetaminophen-dulls-joy/index.html" target="_blank">A study </a>has found that it could reduce pleasure as well. <a href="http://jco.ascopubs.org/content/early/2011/05/06/JCO.2011.34.6346.abstract" target="_blank">Too much of the drug</a> can cause rashes, liver failure and even death.
Photos: Photos: A guide to (legal) pain relief
Acetaminophen – This compound can ease minor muscle, back, tooth and joint pain and reduce fever. Sold under brand names such as Tylenol, Liquiprin and Panadol, it works by regulating the part of your brain that controls your body's temperature and inhibits the synthesis of prostaglandin in the central nervous system. A study has found that it could reduce pleasure as well. Too much of the drug can cause rashes, liver failure and even death.
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Aspirin is one of the cheapest and <a href="http://circ.ahajournals.org/content/123/7/768.extract" target="_blank">oldest manufactured painkillers</a> on the market. German-born scientist <a href="http://www.invent.org/hall_of_fame/184.html" target="_blank">Felix Hoffman</a> is credited with creating and popularizing what was then known as acetylsalicylic acid in 1899 to help ease his dad's arthritis pain. Today, it is used to ease minor aches and headaches. It works by reducing the substance in the body that causes inflammation and fever. Doctors also tell some adults to <a href="http://heart.bmj.com/content/85/3/265" target="_blank">take an aspirin daily</a> to help prevent a heart attack or stroke. People with bleeding conditions like ulcers or cardiovascular troubles like asthma are often advised to take another painkiller, as it may make those conditions worse. Some Americans are also <a href="http://circ.ahajournals.org/content/110/1/e1.full" target="_blank">allergic to aspirin</a>. Americans consume more than 15 billion aspirin tablets a year. Here's a guide to some of the most commonly used pain relief medications:
Photos: Photos: A guide to (legal) pain relief
Aspirin – Aspirin is one of the cheapest and oldest manufactured painkillers on the market. German-born scientist Felix Hoffman is credited with creating and popularizing what was then known as acetylsalicylic acid in 1899 to help ease his dad's arthritis pain. Today, it is used to ease minor aches and headaches. It works by reducing the substance in the body that causes inflammation and fever. Doctors also tell some adults to take an aspirin daily to help prevent a heart attack or stroke. People with bleeding conditions like ulcers or cardiovascular troubles like asthma are often advised to take another painkiller, as it may make those conditions worse. Some Americans are also allergic to aspirin. Americans consume more than 15 billion aspirin tablets a year. Here's a guide to some of the most commonly used pain relief medications:
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