Diverse smallpox strains were widespread in the Viking Age, new study reveals

Tenth century Viking remains found in a mass grave were part of the study.

(CNN)Smallpox, the only human infectious disease to have been successfully eradicated, ailed people at least 1,000 years earlier than previously thought.

A study of DNA sampled from Viking Age skeletons found the presence of smallpox in 11 individuals living in Northern Europe -- what is now Denmark, Sweden, Norway, Russia, and the UK -- between 600 and 1050 AD.
"The 1400-year-old genetic information extracted from these skeletons is hugely significant because it teaches us about the evolutionary history of the variola virus that caused smallpox," professor Eske Willerslev of the University of Cambridge, and director of the University of Copenhagen's GeoGenetics Center, said in a release.
    Prior to this study, the most ancient smallpox viral genomes sequenced were from 17th century Lithuanian mummified remains.
    The findings by an international team of scientists were published on Thursday in Science.
    As Covid-19 continues to rage around the world, learning about ancient epidemics gives us some perspective. Much like us, the Vikings also engaged in long distance travel and commerce.
    "We already knew Vikings were moving around Europe and beyond, and we now know they had smallpox," Willerslev said.
    "People travelling around the world quickly spread Covid-19 and it is likely Vikings spread smallpox. Just back then, they travelled by ship rather than by plane," he added.
    Smallpox killed an estimated 300 million people in the 20th century alone. The disease, caused by the variola virus, covers the body with painful sores. It was declared eradicated in 1980 after a worldwide vaccination campaign launched in 1967 by the World Health Organization.
    In this study, scientists were able to reconstruct four viral genomes from the samples, and found significant differences in the structure of these viruses compared to modern strains. The now-extinct viruses form a group, or clade, of their own.
    "What is really exciting about this is that we can use these reconstructed genomes to trace the steps that these viruses, and other pathogens, took to become the disease that they b