Russia troops have attacked nine settlements, damaging at least eight civilian buildings, including houses and shops, according to the National Police of Ukraine.
Russians fired at the civilian population with “mortars, tanks, artillery, and small arms," and some have been wounded.
The most heavily shelled cities and towns in the region over the past 24 hours have been Mariupol, Marinka, Krasnohorivka, Avdiivka, Vuhledar, Volnovakha, Zalizne, Ocheretyne (Oleksandrivska TG), and Novoselivka-3, according to police. The city of Pokrovsk also came under attack on Wednesday.
Information about destruction and the victims is still being clarified, police say.
The Donetsk region is one of two breakaway eastern Ukrainian territories, the self-declared Donetsk People's Republic and Luhansk People's Republic.