(CNN) — The US Centers for Disease Control and Prevention has moved France to its list of "very high" risk travel destinations.
France and six other countries moved to Level 4, the CDC's highest-risk category, on Monday. France was the world's top destination for international tourist arrivals pre-pandemic, according to 2019 figures from the United Nations World Tourism Organization.
France was joined by European neighbors Andorra, Cyprus, Liechtenstein and Portugal as well as two other places -- one in the Middle East, the other in East Africa -- at Level 4. The seven nations are:
Customers have health passes checked before entering the traditional Christmas market in Strasbourg, France, on December 4, 2021.
Frederick Florin/AFP via Getty Images
Destinations that fall into the CDC's "Covid-19 Very High" Level 4 category have had more than 500 cases per 100,000 residents in the past 28 days.
People should avoid traveling to locations designated with a "Level 4" notice, the CDC recommends. Anyone who must travel should be fully vaccinated first, the agency advises.
In its broader travel guidance, the CDC has recommended avoiding all international travel until you are fully vaccinated.
"Fully vaccinated travelers are less likely to get and spread Covid-19. However, international travel poses additional risks, and even fully vaccinated travelers might be at increased risk for getting and possibly spreading some Covid-19 variants," the agency said.
All of these European destinations, plus Jordan in the Middle East, had previously been considered "high" risk at Level 3. Previously, safari favorite Tanzania had been rated "unknown" for lack of reliable information.
Concerns: Covid surge in Europe and Omicron
The Level 4 announcement comes as two troubling fronts continue to develop in the pandemic.
Secondly, the world is anxiously watching the newest coronavirus variant of concern, called Omicron.
Other nations on Level 4
While Europe is hard hit, it isn't the only region with popular tourist destinations on Level 4. Among the other places also considered at "very high" risk for travel are:
• Cayman Islands
In all, more than 80 countries were rated Level 4 as of December 6.
News from Level 3
Empty roads in Bogota, Colombia, on March 20, 2020. Colombia moved to the CDC's "high" risk category on Monday.
RAUL ARBOLEDA/AFP/AFP via Getty Images
The Level 3 category -- which applies to destinations that have had between 100 and 500 cases per 100,000 residents in the past 28 days -- had four updates this week, all in the Caribbean basin.
The four places moved to Level 3 were:
• Saint Kitts and Nevis
The move was a positive development for the islands of Cuba, Grenada and Saint Kitts and Nevis, which had been at level 4. It's a move in the wrong direction for South America's Colombia, which previously had been at Level 2.
New entries on Level 2
Destinations carrying the "Level 2: Covid-19 Moderate" designation have seen 50 to 99 Covid-19 cases per 100,000 residents in the past 28 days.
It has five new entries this week. They are:
• Cape Verde
• São Tomé and Príncipe
The West African nation of Mali had previously been at Level 1, but rest of the group had been at Level 3. That move down was good news for Fiji, which reopened to international tourists on December 1 for the first time since closing in March 2020.
Level 1 and unknown
The small African nation of Djibouti moved to Level 1 and had previously been at Level 2.
"Level 1: Covid-19 Low" destinations log fewer than 50 new cases per 100,000 residents in the past 28 days.
Finally, there are destinations for which the CDC has an "unknown" risk because of a lack of information. As of December 6, that list included Algeria, Cambodia, Macau and Monaco, among others.