CNN  — 

The United States has begun implementing new rules around travel from China as the coronavirus death toll creeps higher – rules that include re-routing Americans flying into the country to specific airports for screening.

So far, more than 420 people have died in China and more than 19,000 have been infected across more than 25 countries.

In the US, government officials urged residents not to travel to China, issuing a level 4 travel advisory. The World Health Organization (WHO) declared the outbreak a public health emergency of international concern on January 30.

For Americans who traveled there in the past 14 days, the US Department of Homeland Security said there are a total of 11 designated airports – including John F. Kennedy International Airport, Los Angeles International Airport and Hartsfield-Jackson Atlanta International Airport – where travelers can enter the United States.

Those airports, the government said, have more resources to conduct enhanced screening procedures.

If passengers are screened and show no symptoms they will be re-booked to their final destination and asked to “self-quarantine” inside their home, DHS says.

Monday, a spokeswoman for China’s Foreign Ministry accused the US government of inappropriately reacting to the outbreak.

“Even American media and experts doubted the government’s decision, saying that the US government’s restrictions on China are precisely what the WHO rejects, that the US is turning from overconfidence to fear and overreaction, and that banning the entry of foreigners who traveled to China in the past 14 days is suspected to be violating civil rights instead of reducing risks of virus spreading,” Foreign Ministry spokeswoman Hua Chunying said.

What travelers can expect

Based on the new restrictions that went into effect Sunday evening, Americans flying into the United States who have been in China’s Hubei Province in the past 14 days may be subject to up to two weeks of mandatory quarantine, Health and Human Services Secretary Alex Azar said in a news conference.

US citizens who have been in other parts of mainland China in the past 14 days will undergo screening at the designated airports and up to two weeks of monitored self-quarantine, Azar said.

To help expedite that process, DHS acting Secretary Chad Wolf said, Customs and Border Patrol and air carriers will identify passengers who fall under the restrictions before their scheduled flights.

“Once back in the U.S., it’s imperative that individuals honor self-quarantine directives to help protect the American public,” Wolf said in a statement.

The new rules also mean foreign nationals who were recently in China will be temporarily denied entry into the United States, Azar said.

Monday, acting Homeland Security Deputy Secretary Ken Cuccinelli said a Canadian citizen was turned back at the northern border under the new coronavirus travel restrictions. It’s not clear whether anyone else has been turned back as part of the proclamation.

“We’re just beginning, today, to see results of implementation,” Cuccinelli said.

TSA issued new directives

Over the weekend, the Transportation Security Administration (TSA) issued a new directive that requires airlines to ask passengers on flights from outside the United States whether they’ve been to China in the past two weeks.

Chinese nationals coming from China and connecting through another foreign airport will be denied travel, according to a person briefed on the new restrictions. Those with pre-clearance are exempt.

Frontline employees will also be allowed to wear surgical masks if they choose to do so, TSA administrator David Pekoske said in an email directive sent to employees Saturday.

Airlines are suspending travel to China

Meanwhile, airlines around the globe have canceled flights to China amid the outbreak.

Airlines including Delta Air Lines, British Airways, United Airlines, American Airlines, Air Asia, Cathay Pacific, Air India, IndiGo, Lufthansa and Finnair have announced plans to slash the number of flights they are operating to China or stop flying to the country entirely. Many airlines are offering customers refunds or credits.

Delta Air Lines suspended flights Sunday between the United States and China until at least April 30, the airline said in a news release. The suspension went into effect four days earlier than initially planned.

American Airlines also suspended flights between the United States and China, effective January 31 through March 28.

Travelers with upcoming plans should check with their airlines and look for advisories posted on carriers’ websites.

Guidance for American flight crews in China

Over the weekend, the CDC and Federal Aviation Administration (FAA) issued guidance for American-based flight and cabin crews who are traveling or have traveled to China recently.

That guidance includes minimizing their contact with other airport personnel and limiting their time in public while in China, as well as not using public transportation when getting to hotels and monitoring their temperature.

It also directs crews to avoid going into the general population and maintaining a distance of about 6 feet from anyone during their time there.

“Avoid crowds, stores, sporting or mass entertainment events, and other situations likely to attract large numbers of people,” the guidance says.

CNN’s Dakin Andone, Sherisse Pham, Hanna Ziady and Geneva Sands contributed to this report.