The latest on the Covid-19 pandemic and vaccines

By Meg Wagner, Melissa Macaya, Melissa Mahtani, Fernando Alfonso III and Veronica Rocha, CNN

Updated 0148 GMT (0948 HKT) September 23, 2021
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11:12 a.m. ET, September 22, 2021

CDC forecast predicts US Covid-19 hospitalizations will decrease over next 4 weeks 

From CNN’s Naomi Thomas

Paramedics prepare to transport a Covid-19 patient to a hospital in Houston, Texas, on September 15.
Paramedics prepare to transport a Covid-19 patient to a hospital in Houston, Texas, on September 15. (John Moore/Getty Images)

For the second consecutive week, an ensemble forecast from the US Centers for Disease Control and Prevention predicts that new daily Covid-19 hospitalizations will likely decrease over the next four weeks.  

Last week’s forecast, published Sept. 15, predicted hospitalizations would decrease for the first time since the June 23 forecast. 

This week’s forecast predicts that there will be 4,600 to 11,800 new confirmed Covid-19 hospital admissions likely reported on Oct. 18.

According to data from the US Department of Health and Human Services, there were 89,266 people hospitalized with Covid-19 as of Sept. 21. 

The new deaths forecast predicts that deaths will have a stable or uncertain trend over the next four weeks, with a total of 709,000 to 736,000 Covid-19 deaths reported by Oct. 16.

The previous weeks forecast predicted up to 719,000 deaths by Oct. 9

According to data from Johns Hopkins University, there have been 678,522 Covid-19 deaths in the United States. 

The cases forecast predicts 360,000 to 1,290,000 new cases likely reported in the week ending October 16. 

The agency did not forecast whether cases would increase in the next four weeks, something which has not been included since July 28. 

“Case forecasts were not assessed for likely increases or decreases because more reported cases than expected have fallen outside the forecast prediction intervals,” the forecast said.

10:26 a.m. ET, September 22, 2021

CDC's vaccine advisers are meeting now on Covid-19 boosters

From CNN's Jamie Gumbrecht

The CDC headquarters in Atlanta, Georgia.
The CDC headquarters in Atlanta, Georgia. (Elijah Nouvelage/Bloomberg/Getty Images)

The US Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) is meeting now, and the committee will hear presentations on Covid-19 vaccine booster doses from CDC experts and Pfizer, as well as presentation on vaccine effectiveness and vaccine safety during pregnancy.

They are scheduled to meet today until 4:30 p.m. ET and tomorrow from noon to 3:30 p.m. ET.

No vote is currently on the agenda today or tomorrow.

The US Food and Drug Administration is still considering a booster dose of the Pfizer/BioNTech Covid-19 vaccine after a lengthy discussion among its advisers on Friday.

If the FDA authorizes booster doses of Pfizer’s vaccine ahead of tomorrow’s ACIP meeting, the CDC committee could vote on whether to recommend the doses for use.

9:08 a.m. ET, September 22, 2021

White House announces US will send additional 500 million doses of vaccines to other nations in 2022

From CNN's Jason Hoffman 

The United States is set to significantly increase the amount of Covid-19 vaccines it will ship to foreign nations beginning in 2022 in an effort to end the pandemic worldwide, the White House announced Wednesday.

As part of today's virtual Covid-19 summit on the margins of the UN General AssemblyPresident Biden will announce that the US is purchasing an additional 500 million Pfizer Covid-19 vaccines to donate to low- and lower-middle-income countries around the world, a senior administration official said, previewing the summit. The newly announced 500 million doses are on top of the 500 million the US had already committed to sharing with other nations.

Those vaccines will begin shipping out in January, and from January through September of next year, the US will ship out 800 million vaccines to the world, the official said. These vaccines bring the United States total to over 1.1 billion vaccines donated to other countries.

"The President's strategy from day one has been to take care of Americans and to help vaccinate the world, and that's why even as we mounted an unprecedented domestic vaccination program here, we purchased 500 million vaccine doses for the sole purpose of giving them to others," the official said, adding that the US will now double that commitment even as the country continues to vaccinate Americans and prepare for potential booster shots.

The official said that the additional 500 million vaccines will be purchased at a not-for-profit price and will be distributed through Covid-19 Vaccines Global Access, the global vaccination program known as COVAX.

"We're proving that you can take care of your own, while helping others as well. We can and we must do both," the official said.

Read more about today's Covid-19 summit here.

10:03 a.m. ET, September 22, 2021

How global vaccine inequality was highlighted at the UN General Assembly

From CNN's Eliza Mackintosh

President Joe Biden addresses the United Nations General Assembly on September 21.
President Joe Biden addresses the United Nations General Assembly on September 21. (Eduardo Munoz/Pool/Getty Images)

US President Biden called for a new era of international cooperation to fight the pandemic in his debut address to the United Nations General Assembly, but, one year after world leaders pledged to bring Covid-19 vaccines and treatments to “all people, everywhere,” the message of unity rang empty. 

Speaking to a much smaller crowd than usual due to the ongoing coronavirus crisis, Biden on Tuesday urged heads of state to take swift action to rein in a pandemic that has killed millions and continues to resurge. 

“We need a collective act of science and political will,” he said to a hybrid audience of virtual and in-person UN delegations. “We need to act now to get shots in arms as fast as possible, and expand access to oxygen, tests, treatments, to save lives around the world.” 

On Wednesday, the White House said it was set to send an additional 500 million doses of Covid-19 vaccines to foreign nations in 2022.  

But the ongoing debate over how best to address the wide gap in vaccine access is boiling over at the UN, with national leaders condemning vaccine abundance in rich nations like the US and the drip-feed of shots afforded to the rest of the world. 

President Rodrigo Duterte of the Philippines on Tuesday accused rich countries of hoarding Covid vaccines while the poor “wait for trickles” and developing countries consider half-doses to cover more of their populations. The Philippines has one of the lowest Covid vaccination rates in Asia, with just 17% fully vaccinated. 

The divide, Duterte said in a prerecorded speech, “is shocking beyond belief – it must be condemned for what it is, a selfish act that can neither be justified rationally nor morally.” 

Speaking to CNN on Sunday, UN Secretary-General Antonio Guterres highlighted Biden’s Covid-19 summit on the UNGA sidelines and an International Monetary Fund proposal to create a $50 billion vaccine program for poor countries, saying these were “positive signs” that rich nations were starting to work together to tackle vaccine inequity. 

"But let's be clear: All this is too little, too late," he added. 

Out of six billion doses administered worldwide, only 2% have been in low-income countries. Discussions around how many traveling diplomats might still be unvaccinated illustrated just “how dramatic” the disparity in distribution remains, Guterres told Reuters. In a new take on vaccine diplomacy, a free Covid-19 testing and vaccination van welcomed world leaders and delegates at the UN, with the aim of avoiding a super-spreader event. 

A so-called “honor system” calling for foreign delegations to be vaccinated before entering the assembly hall was broken on the very first day of the General Assembly. 

8:52 a.m. ET, September 22, 2021

CDC advisory committee will discuss vaccine boosters today following FDA advisers vote last week

From CNN's Maggie Fox, Jamie Gumbrecht and Jacqueline Howard

The US Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (ACIP) is holding a two-day meeting on Wednesday and Thursday on booster shots.

Wednesday’s meeting will include a discussion on booster doses of Pfizer’s Covid-19 vaccine, vaccine effectiveness in the US and vaccine safety in pregnant women.

Wednesday's meeting comes after the vaccine advisers to the US Food and Drug Administration voted Friday to recommend emergency use authorization of a booster dose of Pfizer's vaccine to people 65 and older and those at high risk of severe Covid-19 six months after they get their first two shots.

But the FDA's Vaccines and Related Biological Products Advisory Committee rejected a broader application to approve booster doses of Pfizer's vaccines for everyone 16 and older six months after they are fully vaccinated.

Members of the committee expressed doubts about the safety of a booster dose in younger adults and teens, and complained about the lack of data about the safety and long term efficacy of a booster dose.

Biden administration officials had previously announced a plan to begin administering booster doses to the general population during the week of Sept. 20, irritating some members of the committee. They later noted that any action would be pending signoff from the FDA and the CDC.

The CDC must give its stamp of approval for any booster doses to be officially given. In a letter sent last Thursday and obtained by CNN, the CDC urged local and state health officials to wait to administer boosters until both agencies had signed off.

Third doses are already approved for certain immunocompromised people, but not for the general public.

9:45 a.m. ET, September 22, 2021

Here's how soon the FDA could authorize Covid-19 vaccines for young children, according to one expert

From CNN's Madeline Holcombe

(Ben Hasty/MediaNews Group/Reading Eagle/Getty Images)
(Ben Hasty/MediaNews Group/Reading Eagle/Getty Images)

The US Food and Drug Administration (FDA) could soon authorize a Pfizer/BioNTech Covid-19 vaccine for young children, experts said — a development that offers hope in the midst of a dangerous time in the pandemic for kids, who account for a quarter of all cases reported last week.

"It is conceivable that by Halloween, we could see shots going into arms, but it's going to take a number of weeks for that process to work its way through," Dr. James Hildreth, a vaccine adviser to the FDA, told CNN's Don Lemon Monday.

That process is happening as the second highest total of new cases in children was reported last week and cases among that group continue to rise exponentially, according to data from the American Academy of Pediatrics published Monday.

And as cases spread, hospitalization rates are high. An average of 311 children were hospitalized with Covid-19 every day over the past week, according to data from the US Centers for Disease Control and Prevention (CDC).

In Pittsburgh, officials at UPMC Children's Hospital said they are seeing a "historic" number of children coming to the Emergency Department. A tent was set up outside the emergency room Friday to help accommodate more patients, the hospital said in a social media post.

Currently, the youngest Americans eligible for vaccination are 12 year olds, and the vaccination rate of adolescents is still inching toward the halfway mark, according to a CNN analysis of data from the CDC.

Where things stand now: Trials are currently underway for younger children, and Pfizer/BioNTech announced in a news release Monday that a Phase 2 of 3 trial showed their two-dose vaccine was safe and generated a "robust" antibody response in children 5 to 11.

The expansion of vaccine access would be important both for protecting children and for ending the hold the virus has on the US for everyone, dean of the National School of Tropical Medicine at Baylor College of Medicine, Dr. Peter Hotez said.

"Ultimately, if we're serious about halting this epidemic in the United States, we need 85-90% of the US population vaccinated," Hotez said. "That means all of the adults, all of the adolescents and large numbers of young kids."

But there is still a big challenge ahead: getting the doses into kid's arms, CNN medical analyst Dr. Johnathan Reiner said.

8:53 a.m. ET, September 22, 2021

Biden will host a global virtual Covid-19 summit today

The Covid-19 pandemic was a central focus of President Biden's speech yesterday before the United Nations General Assembly.

Biden argued that the global community's response to pressing challenges like the climate crisis and the Covid-19 pandemic will "reverberate for generations yet to come."

"Indeed, today many of our greatest concerns cannot be solved or even addressed through the force of arms. Bombs and bullets cannot defend against Covid-19 or its future variants. To fight this pandemic, we need a collective act of science and political will. We need to get shots in arms as fast as possible and expand access to oxygen, tests, treatments to save lives around the world," he told world leaders.

Biden touted the US shipping more than 160 million Covid-19 doses to countries around the world and putting more than $15 billion toward the global pandemic response

"Planes carrying vaccines from the United States have already landed in 100 countries, bringing people all over the world a little dose of hope as one American nurse termed it to me. A dose of hope, direct from the American people, and importantly, no strings attached," the President said.

Biden said that he'd be announcing additional commitments at a US-hosted virtual global Covid-19 summit today as the country "seeks to advance" the fight against Covid-19 and "hold ourselves accountable around specific targets on three key challenges."

Biden listed those challenges as:

  1. Saving lives now
  2. Vaccinating the world
  3. Building back better

CNN's Kate Sullivan, Maegan Vazquez and Kevin Liptak contributed reporting to this post.