November 21 coronavirus news

By Ben Westcott, Adam Renton, Rob Picheta and Meg Wagner, CNN

Updated 0025 GMT (0825 HKT) November 23, 2020
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1:19 a.m. ET, November 21, 2020

US reports more than 195,000 new Covid-19 cases -- a record one-day total for the second straight day

From CNN's Rebekah Riess

The United States reported 195,542 new Covid-19 cases on Friday, according to Johns Hopkins University, the second consecutive day that the country has posted its highest one-day total of the pandemic.

The previous daily high was recorded on Thursday with 187,833 cases.

A further 1,878 virus-related fatalities were also reported Friday.

At least 11,910,858 Covid-19 cases, including 254,413 deaths, have now been reported nationwide.

The totals include cases from all 50 states, the District of Columbia and other US territories, as well as repatriated cases.

CNN is tracking the US cases:

12:57 a.m. ET, November 21, 2020

Navajo Nation reports a record number of new Covid-19 cases

From CNN’s Andy Rose

The Navajo Nation reported 351 new coronavirus cases Friday, surpassing the previous one-day record set in May by 47%.

“This is not only devastating, but it indicates that the uncontrolled spread of the virus is impacting all communities on the Navajo Nation and in nearby border towns and cities,” President Jonathan Nez said in a written statement.

It comes as the Navajo Nation is under a three-week “stay-at-home lockdown,” with most businesses closed and residents told to remain in their homes, except for emergencies and essential activities.

The nation’s total number of positive cases since the start of the pandemic is 14,441. The Navajo Nation is located within parts of Arizona, New Mexico, and Utah.

“Our health care system is struggling and may soon be overwhelmed,” said Navajo Nation Vice President Myron Lizer. “We have to do everything within our power to protect our children, elders, and those with existing health conditions.”

12:33 a.m. ET, November 21, 2020

Most coronavirus cases are spread by people without symptoms, CDC now says

From CNN's Maggie Fox

A sign reminding people to wear masks is seen by the pier on September 7 in Manhattan Beach, California.
A sign reminding people to wear masks is seen by the pier on September 7 in Manhattan Beach, California. Chris Delmas/AFP/Getty Images

Most coronavirus infections are spread by people who have no symptoms, the US Centers for Disease Control and Prevention said in newly updated guidance.

It's one of the main reasons mask use is so important, the CDC said.

"Most SARS-CoV-2 infections are spread by people without symptoms," the agency said in a section of its website devoted to explaining the science of how to use masks to control the spread of the virus.

"CDC and others estimate that more than 50% of all infections are transmitted from people who are not exhibiting symptoms," it added in the guidance posted Friday.
"This means at least half of new infections come from people likely unaware they are infectious to others."

According to the CDC, 24% of people who transmit the virus to others never develop symptoms and another 35% were pre-symptomatic. It also said 41% infected others while experiencing symptoms.

Read more:

12:01 a.m. ET, November 21, 2020

Japan reports new daily high of Covid-19 cases for a third straight day

From CNN's Yoko Wakatsuki in Tokyo

Commuters queue in line to wait for a bus during rush hour in Tokyo, Japan on November 20.
Commuters queue in line to wait for a bus during rush hour in Tokyo, Japan on November 20. Eugene Hoshiko/AP

Japan recorded a daily high increase of new coronavirus cases for the third day in a row on Friday.

The country's Health Ministry announced there had been 2,427 new coronavirus infections and 20 deaths in the past 24 hours.

The nationwide toll currently stands at more than 128,377 Covid-19 cases and at least 1,976 fatalities.

Osaka prefecture also reported another daily high with 370 new cases.

Osaka Gov. Yoshifumi Yoshimura asked residents Friday to avoid dining with more than five people and for longer than two hours for the next two weeks. The Osaka government also asked that high-risk elderly citizens only make essential outings during the same period.

Japan's capital Tokyo added 522 new cases, bringing the city's total to 36,778. 

10:30 p.m. ET, November 20, 2020

The US has reported more than 193,000 cases so far for Friday-- a new daily high for the second straight day

From CNN's Dave Alsup

A healthcare worker administers a free Covid-19 test to a person in a car at the Columbus West Family Health and Wellness Center in Columbus, Ohio on November 19.
A healthcare worker administers a free Covid-19 test to a person in a car at the Columbus West Family Health and Wellness Center in Columbus, Ohio on November 19. Stephen Zenner/AFP/Getty Images

The United States has reported 193,079 Covid-19 cases so far on Friday, according to Johns Hopkins University, the highest one-day total of the pandemic for a second consecutive day.

The previous daily high was recorded on November 19, with 187,833 cases.

At least 11,908,395 Covid-19 cases, including 254,383 deaths, have now been reported nationwide.

The totals include cases from all 50 states, the District of Columbia and other US territories, as well as repatriated cases.

Note: The numbers are not the final count for the day, and could rise further.

CNN is tracking the US cases:

10:31 p.m. ET, November 20, 2020

Canada's largest city is going into lockdown for at least 28 days

From CNN's Gisela Crespo

Shoppers walk through the Eaton Centre in Toronto on November 20. Retail will be allowed to operate for curbside pick-up or delivery only under lockdown rules that take effect Monday.
Shoppers walk through the Eaton Centre in Toronto on November 20. Retail will be allowed to operate for curbside pick-up or delivery only under lockdown rules that take effect Monday. Steve Russell/Toronto Star/Getty Images

Toronto, Canada's biggest city, is going into lockdown for at least 28 days to limit the spread of Covid-19, according to a news release from the Office of the Premier of Ontario published Friday. 

The lockdown will go into effect Monday and it includes Peel Region, which is part of the Greater Toronto Area. 

Ontario Premier Doug Ford said in the news release that Covid-19 numbers are "rising rapidly in certain regions," adding the lockdown will protect "hospitals, long-term care and retirement homes, and every person in this province." 

"We cannot afford a province-wide lockdown, so we are taking preventative action today by moving Toronto and Peel into lockdown level restrictions ... We need to take decisive action to stop the spread of this deadly virus," Ford said. 

These are the lockdown rules:

  • Indoor social gatherings or events won't be allowed except with members of the same household, and outdoor gatherings will be limited to no more than 10 people, according to the release. 
  • Wedding services, funerals, and religious ceremonies where physical distancing can be maintained indoors or outdoors will also be limited to no more than 10 people. 
  • Retail will be allowed to operate for curbside pick-up or delivery only. Certain businesses such as grocery stores and pharmacies will be allowed to open at 50% capacity. 
  • Schools and childcare will remain open, and post-secondary education will move to virtual learning except for training that can only be provided in person. 

Other parts of the province will move to higher levels of restrictions starting Monday as well, according to the release. 

9:11 p.m. ET, November 20, 2020

FDA announces advisory committee to meet to discuss Pfizer's vaccine application in December

From CNN's Ben Tinker and Maggie Fox

The US Food and Drug Administration said Friday it has scheduled a meeting of its outside advisory panel to discuss Pfizer and BioNTech’s application for emergency use authorization for a coronavirus vaccine.

The Vaccines and Related Biological Products Advisory Committee (VRBPAC) will meet on Dec. 10. 

The companies submitted their application for an EUA earlier Friday. It’s the first application for an FDA regulatory OK for a coronavirus vaccine.

"The FDA recognizes that transparency and dialogue are critical for the public to have confidence in Covid-19 vaccines. I want to assure the American people that the FDA's process and evaluation of the data for a potential Covid-19 vaccine will be as open and transparent as possible," FDA Commissioner Dr. Stephen Hahn said in a statement.

"The FDA has been preparing for the review of EUAs for Covid-19 vaccines for several months and stands ready to do so as soon as an EUA request is submitted. While we cannot predict how long the FDA's review will take, the FDA will review the request as expeditiously as possible, while still doing so in a thorough and science-based manner, so that we can help make available a vaccine that the American people deserve as soon as possible.”

The FDA is supposed to post the VRBPAC meeting schedule in the Federal Register at least two weeks ahead of time. The agency has promised to fully consider input from the committee, which is made up of vaccine experts and others with no ties to the companies submitting vaccines for FDA approval or authorization.

“A discussion about the safety and effectiveness of Pfizer and BioNTech's vaccine with this committee, made up of outside scientific and public health experts from around the country, will help ensure clear public understanding of the scientific data and information that the FDA will evaluate in order to make a decision about whether to authorize a vaccine for emergency use for the prevention of Covid-19,” Hahn said.

The FDA said it will livestream the VRBPAC meeting on the agency's YouTube, Facebook and Twitter channels and from the FDA website.

10:33 p.m. ET, November 20, 2020

Donald Trump Jr. tests positive for coronavirus

From CNN's Kaitlan Collins and Veronica Stracqualursi

Donald Trump Jr. attends a book signing to promote his book "Liberal Privilege"in Long Island, New York, on Sunday, October 18.
Donald Trump Jr. attends a book signing to promote his book "Liberal Privilege"in Long Island, New York, on Sunday, October 18. Lokman Vural Elibol/Anadolu Agency/Getty Images

Donald Trump Jr., President Donald Trump's eldest son, has tested positive for the coronavirus, a personal spokesman told CNN on Friday.

"Don tested positive at the start of the week and has been quarantining out at his cabin since the result," the spokesman said. "He's been completely asymptomatic so far and is following all medically recommended COVID-19 guidelines."

Bloomberg was first to report Trump Jr.'s positive result.

Trump Jr. becomes the latest figure close to the President to test positive for Covid-19. In addition to himself, first lady Melania Trump, his youngest son Barron, his chief of staff Mark Meadows and a number of other top aides both in his campaign and in the White House have tested positive in recent months.

Read more:

7:51 p.m. ET, November 20, 2020

Pfizer and BioNTech apply for FDA emergency use authorization for coronavirus vaccine

From CNN's Jamie Gumbrecht

Pfizer and BioNTech on Friday submitted to the US Food and Drug Administration for emergency use authorization for their coronavirus vaccine candidate.

This is the first coronavirus vaccine to seek regulatory clearance in the United States.

"It is with great pride and joy and even a little relief that I can say that our request for emergency use authorization for our Covid-19 vaccine is now in the FDA's hands," Pfizer CEO Albert Bourla said in a video shared on Friday. "This is a historic day, a historic day for science and for all of us. It took just 248 days to get from the day we announced our plans to collaborate with BioNTech to our FDA submission day.
"We have operated at extraordinary speed in our clinical development program, from concept to regulatory filing, while always maintaining our focus on safety."

The vaccine, known as BNT162b2, could potentially be available for use in high-risk populations in the United States by the middle to end of December, Pfizer and BioNTech said in a statement earlier Friday. The vaccine requires two doses a few weeks apart, and protection is achieved 28 days after the first shot.

The submission to the FDA is based on results from the Phase 3 clinical trial of Pfizer's vaccine, which began in the United States on July 27 and enrolled more than 43,000 volunteers.

The final analysis from the trial found the coronavirus vaccine was 95% effective in preventing infections, even in older adults, and caused no serious safety concerns, Pfizer and BioNTech said this week. The submission also includes safety data on about 100 children ages 12 to 15.

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