The latest on the coronavirus pandemic and vaccines

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, told CNN’s John Berman that to make a difference in the vaccine rollout, they need to get into local areas to understand what’s going wrong and how to fix it.

“It’s a complicated issue,” Fauci said when asked one thing he would like to see today to make a difference on vaccinations.

“You got to get into the local area and find out what’s going on here, what’s wrong, let’s try and fix it,” he said.

“Back months ago, for example when you’re sitting in the situation room and you hear, OK, things look pretty good, you know this is happening, that’s happening. You go home, you get on the phone to the people who are actually doing it and they say it’s not working well.” 

Fauci said that they need to go the local areas and partner with people doing vaccinations to look at what went wrong there and how they can help them to fix things — or help them to help themselves fix it. 

“I think that’s what you’re going to be starting to see, in fact it’s happening right now,” he said. 

If you aren’t sure of what’s going wrong, “don’t guess, go and figure out what it is and help people fix it,” he said.

The European Union will seek clarification from Pfizer on reports of new delays in delivering Covid-19 vaccines, chief spokesperson for European Commission Eric Mamer said during a press briefing on Friday.

Mamer stressed that the Commission is constantly in contact with the manufacturers and are aware of recent developments.

Last week Pfizer said that shipments from its vaccine facility in Puurs, Belgium, would be temporarily reduced as it scales up to produce 2 billion Covid-19 vaccine doses in 2021.  

Eric Mamer explained that the deliveries are organised specifically between the Member States and the companies, while the Commission supports the relationship between the two. 

Some background: Italy announced Wednesday it will take legal actions against pharmaceutical company Pfizer over Covid-19 vaccine delays.

"Unfortunately this week we received 29% fewer vaccine jabs from Pfizer and we have been told that we will receive 20% fewer vaccine jabs next week," the country’s extraordinary coronavirus commissioner Domenico Arcuri said Thursday during a press conference. The vaccination rollout has been "significantly" slowed down due to this delay, Arcuri added.

"Until last Saturday we vaccinated an average of 80,000 people a day, with a peak of 92,618 in 24 hours. After Saturday, the people who were vaccinated are just over a third, 28,000 on average," he said.

Pfizer said last week that in order to increase capacity, changes were needed to the process and facility, and additional regulatory approvals would be required.

Pfizer's vaccine partner BioNTech later said that the original schedule for deliveries to the European Union would resume the week beginning Jan. 25.

BioNTech said it hoped to “increase delivery beginning the week of February 15," which would result in delivering “the fully committed quantity of vaccine doses in the first quarter and significantly more in the second quarter."

The British government has denied reports that suggest that it intends to pay everyone in England who test positive for Covid-19 and additional £500 (which is about $683), in an effort to increase the number of people respecting lockdown rules.

"We've given local authorities £70 million for the scheme and they are able to provide extra payments on top of those £500 if they think it necessary,” the spokesperson also said.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, told CNN’s John Berman Friday that he thinks that the country will do better than the goal of 100 million vaccine doses administered in President Joe Biden’s first 100 days in office. 

Fauci said that you go for 100 million over 100 days, “if we do better than that, which I personally think we likely will, then great.”

“We’re just going to go for it for as much as you possibly can,” Fauci said. “When you set a goal, if you do better than the goal, that’s terrific, I hope we do.” 

Some background: US President Biden has pledged to provide 100 million doses of Covid-19 vaccine in his first 100 days of office. 

White House coronavirus coordinator Jeff Zients said Thursday he thinks the vaccine supply will be adequate to meet this goal.

The Ukrainian capital of Kiev is negotiating with several manufacturers to purchase one million vaccine doses, Mayor Vitali Klitschko said during a briefing on Friday.

“It is a question of buying 1 million doses for the vaccination of 500,000 Kyiv residents,” he added.

The mayor stressed that the capital is ready to buy the vaccine with the money from the city budget.

City authorities have preliminary agreements with some manufacturers and the capital has an infrastructure ready for vaccination: there is equipment for storing the vaccine, vaccination rooms, and specialists who will conduct centralized training, Klitschko said.

"We must prevent the spread of the disease. First of all, to protect the most vulnerable categories of the population,” he emphasized.

For background: Covid-19 vaccination has yet to begin in Ukraine. President Volodymyr Zelensky said last week the European Union should pay increased attention to the Eastern Partnership countries in purchasing and supplying the Covid-19 coronavirus vaccine.

As of Friday, the country reported 5,348 new coronavirus cases and 163 new daily deaths, Health Minister Maksym Stepanov said on his official Facebook page.

The current death toll currently stands at 21,662, whilst the total number of cases recorded since the pandemic began is now 1,182,969, according to the government's dashboard.

Spanish soccer giants Real Madrid announced in a statement on Friday that manager Zinedine Zidane has tested positive for Covid-19.

The club did not provide any further details.

The Frenchman was present on the touchline as Real fell to a humiliating defeat to third-division club Alcoyano in the Spanish Copa del Rey on Wednesday.

Zidane guided Real to their first La Liga title in three years last season after having previously led them to three consecutive UEFA Champions League successes in 2016, 2017 and 2018 and one league title in 2017, among others, in his first spell in charge.

Real currently sit second in the league, seven points behind local rivals Atletico Madrid, having played a game more.

The team is scheduled to play Alavés away in La Liga on Saturday.

Here are some of the key coronavirus lines from Europe today:

It probably won’t make a big difference if people can’t get a second Covid-19 vaccine until six weeks after the first, Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said Friday.

On Thursday, the US Centers for Disease Control and Prevention updated its guidance to say that people could schedule second doses of vaccine up to six weeks after their first if they were unable to get it in the recommended time frame -- 21 days after the first shot for the Pfizer vaccine, or 28 days after the first shot for the Moderna vaccine.

On Thursday, Fauci told CNN’s Chris Cuomo that people were “taking a chance” if they waited up to six weeks, although it was possible it was “not going to be a big deal.”

Fauci explained to CNN’s John Berman on New Day Friday that clinical trial said it’s optimal to stick with the recommended time frames. What the CDC is saying, Fauci said, is “sometimes the situation is stressed, where it’s very difficult to be exactly on time. So, we’re saying you could probably do it six weeks later, namely two additional weeks.” 

He said that “quite frankly, immunologically, I don’t think that’s going to make a big difference.”

“I don’t see a big problem with that if the situation on the ground means the stress is such you can’t precisely do 28 days or 21 days,” Fauci said.

He said that there is no disagreement between the CDC and himself: “They’re saying, practically speaking, if you gotta do that, it very likely is not going to make a big difference.”

Watch more from Fauci's interview with CNN here:

The US Centers for Disease Control and Prevention [CDC] did not meet a goal to quickly ramp up surveillance for possibly dangerous coronavirus mutations, according to numbers from the federal agency.

At the beginning of the year, Dr. Gregory Armstrong, director of the CDC’s Office of Advanced Molecular Detection at the National Center for Emerging and Zoonotic Infectious Diseases, told CNN he hoped that over the next two weeks that the agency would more than double the number of coronavirus genomes being sequenced in the US. While the number of sequences did increase over those two weeks, it did not double.  

The hope was to sequence an additional 3,500 coronavirus samples per week. But only 2,250 to 2,650 additional samples were sequenced, according to CDC numbers, with more expected soon as private labs have recently come online to help in the effort.

Hunting for new mutations is a critical part of combatting the spread of the virus. While most mutations are harmless, some might be able to spread more quickly, be more deadly, or be resistant to coronavirus vaccines. 

The US has been criticized for having a lackluster sequencing program. Last week, President-elect Joe Biden said he would increase funding for coronavirus surveillance efforts when he takes office.  

“We simply do not have the kind of robust surveillance capabilities that we need to track outbreaks and mutations,” according to a Biden’s American rescue plan issued last week. 

The US ranks 33rd in the world for sequences per 1,000 cases of Covid-19, falling behind countries that have far fewer resources, such as Senegal and Sierra Leone, according an analysis by the Broad Institute of Harvard and the Massachusetts Institute of Technology using data from GISAID, an independent data sharing initiative. 

Hotez added that when it comes to genomic sequencing, the US comes up “profoundly small, and that’s tragic. And it’s costing American lives.”

Read the full story here.